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Heather Smith-Fernandez: Improving the condition of our mitochondria and improving efficient output of cellular energy has widespread effects, and in some cases, these effects are palpable (we actually feel more energy, more focus, less pain, more endurance)

Furthermore, elevated levels of pro-inflammatory interferon (IFN-), tumor necrosis factor (TNF-), and granzyme B (produced by CD8 + T cells) increased the IFN- level in the adipose tissue of middle-aged mice [11]

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The recent identification of CHCHD2 and UQCRC1 that are critical for functions of complex IV and complex III, respectively, provide direct evidence that PD is more than just a complex I disorder